Analytical Electron Tomography: Methods and Applications

New methods for electron tomography

Transmission electron microscopy images acquired under tilted-beam conditions experience an image shift as a function of defocus settings—a fact that is exploited as a method for defocus determination in most of the automated tomography data collection systems. While the method was shown to be highly accurate for a large variety of specimens, we point out that in its original design it can stri...

Geometric reconstruction methods for electron tomography.

Electron tomography is becoming an increasingly important tool in materials science for studying the three-dimensional morphologies and chemical compositions of nanostructures. The image quality obtained by many current algorithms is seriously affected by the problems of missing wedge artefacts and non-linear projection intensities due to diffraction effects. The former refers to the fact that ...

Hemoglobin A1c: Clinical applications and analytical considerations

Diabetes Mellitus (DM) is the most common disorder of carbohydrate metabolism. Hyperglycemia is the common feature of DM. Hyperglycemia causes cardiovascular, renal, ocular, and peripheral nerve disorders in patients with diabetes. Glycemic regulation plays an essential role in controlling these complications. Thus, evaluation of the glycemic control status is crucial in the management of DM. H...

Sequential Methods and Their Applications

Recent advances in electron tomography: TEM and HAADF-STEM tomography for materials science and semiconductor applications.

Electron tomography is a well-established technique for three-dimensional structure determination of (almost) amorphous specimens in life sciences applications. With the recent advances in nanotechnology and the semiconductor industry, there is also an increasing need for high-resolution three-dimensional (3D) structural information in physical sciences. In this article, we evaluate the capabil...